Successfully complete the game to unlock the "Nightmare Mode" option at the Special Features screen.
Successfully complete the game with any character to unlock the "Alternate Hunter Mode" option at the Special Features screen. Activating "Alternate Hunter Mode" gives the four playable characters different costumes.
Save at least fifty innocents before returning to the train to unlock the good ending.
It is best to stay near Hadrian (the opponent with the talking arm). If you move in the room while fighting him, two of the first level Bosses (with many arms) and four of the enemies that hit you with their eyelashes (with 2 legs) will attack.
Use Judge. His crossbow kills them in one shot. Note: This refers to the white ladies that have machine guns and can move very fast, and not the Boss to the mansion.
On the levels after Arkady when the blue wolves chase you, do not waste any ammunition or conviction on them. Save it up for the werewolf, and use special weapons or conviction on him. You will need all the items you can get for the last Boss, especially if you do not have a lot of lives or are Martyl or Defender.
To defeat the Boss with Judge, use WordOfPower. When Judge's conviction disappears, go up close with the sword and slash. The Boss will kill you, but you will return with more conviction. Then, use WordOfPower and repeat. To defeat the Boss with Judge and Defender, use the same as with just Judge, but have Defender get all the special weapons on the level. While Judge does his attacks, have Defender stay back and shoot. When fighting the Mansion Boss, keep yourself directly behind him and kill him using any weapon. He cannot hurt you from that position unless he turns around and faces you. The key is to face his back. The easiest and fastest to kill the Mansion Boss is with a chainsaw. Get behind him as much as possible and use the chainsaw completely to kill him quickly.
As any character, grab the machine gun at the lower left of the screen. Use any weapon to hurt the Boss. When he goes to recharge, run to the big window in the room and unload your Uzi, Shotgun, Chainsaw, or other weapon into it until it breaks open and the Boss dies. You can pretty much ignore him when he returns from getting charged, since you will be standing on a Health Glyph while destroying the window. Vampire and sunlight equals death. When you get to the last Boss, do not free the three locked up innocents unless you have low remaining lives. Freeing them will make the Boss have two more images of himself, creating three Bosses, but only one will be real.
Load up your rocket launcher before you go in the electric chair room. Run to the middle of the room, avoiding him. Run around in circles with the Launcher pointed at the chair. Keep shooting it while you run in circles. Make your circles just big enough to avoid him and do not accidentally shoot him at point blank range or you will lose a life. Change your direction when he changes his. The chair should explode after awhile. You can then just shoot him at your leisure or slice him up a bit before regenerating your health. You should be able to kill him without losing a life.
When you enter the room with the two sisters/innocents, defeat all the enemies but do not leave. Search the walls in that room and find the spot where the wall is cracked. Attack it with any weapon. It will eventually collapse. Inside are some special weapons (shotgun, etc.) and the permanent strength power-up.
In the catacombs, if you do not see the crack, slice at the wall that points north from the screen. It should give off white puffs when attacking the correct wall.
When there are many enemies in your area, use the cleave axe special. Go in the middle of them, hold R, then release. This will take out many of the nearby enemies.
Choose Judge when playing the game in single player mode. Note: The flaming crossbow arrows visible in the FMV sequence are not actually in the game.
Activating the Demand Edge harms your hunter -- use it sparingly.
Defender's Healing Edge can heal all Hunters near her when it gets to level 2 and 3. Note: On level 2, hunters must come close to Defender. On level 3, Hunters can be a few steps away.