Enter "SAVAGELAND" as a code to unlock all Fantastic 4 comics.
Enter "NZONE" as a code to unlock all Tomorrow People comics.
Enter "THEHAND" as a code to unlock the Electra swimsuit card.
Enter "REIKO" as a code to unlock Solara swimsuit card.
Enter "MONROE" as a code to unlock the Storm swimsuit card.
Enter "HOWLETT" as a code to unlock the Wolverine trading card.
In Versus mode, fight as Spider-Man vs. Venom (CPU) in the NYC bridge arena. Win to unlock the Daily Bugle Rooftop arena. Note: You may need to first complete the game.
Successfully complete the Iron Man 3 mission in Story mode to unlock Brigade.
Successfully complete the Daredevil 3 mission in Story mode to unlock Daredevil.
Successfully complete the Storm 3 mission in Story mode to unlock Fault Zone.
Successfully complete the Magneto 3 mission in Story mode to unlock Hazmat.
Successfully complete the Iron Man 3 mission in Story mode to unlock Iron Man.
Successfully complete the Magneto 3 mission in Story mode to unlock Magneto.
Successfully complete the Paragon 3 mission in Story mode to unlock Paragon.
Successfully complete the Venom 3 mission in Story mode to unlock Solara.
Successfully complete the Storm 3 mission in Story mode to unlock Storm.
Successfully complete the Paragon 4 mission in Story mode to unlock Van Roekel.
Successfully complete the Venom 3 mission in Story mode to unlock Venom.
Every ten versus battles unlocks either a venue or a character. The easiest way to do this is on the Bridge level, with a second controller. Throw your opponent off the edge of the bridge to get an easy victory. Additionally, use Spider Man's web throwing move against an idle player two. Keep selecting "Rematch" to speed up the process.
This works best when you are in Rage mode. When in Rage mode, damage your opponent down to danger. Then, try to get next to your opponent and do a Super Block (R + Y) to knock them off guard. Then, quickly press R + X to do the finishing move.
While playing as Spider-Man, Daredevil, Elektra, or anyone else that does handsprings for a dodging move, hold Y and press Analog-stick Away or Analog-stick Forward. Keep tapping in that direction and your character will keep doing handsprings.
Win the indicated number of versus match to unlock the corresponding bonus: