Collect all 50 Spider Emblems to unlock the Black Spider-Man suit to wear anytime desired without any negative effects.
Choose any of the gang patrol missions (Apocalypse, Dragon Tail, H-Bombers, Waste Tribe), and defeat all of their marked territories that match their logos to earn 3 experience points.
Play through Story mode and take every boss' picture and any gang members desired, but make sure to leave at least one. After completing Story mode, take any remaining pictures you have not taken to get around 15 Hero Points. Then, save the game and reset your Wii. Load your saved game file and you should hear and see the Villain Photos complete and get another 15 Hero Points. Spend them, save, and repeat the process as many times as desired.
Immediately after you defeat Sandman for the first time in the "Mary Jane's Favorite Band" mission and before you "Meet Mary Jane At The Restaurant", you cannot take off the Black suit. During this time period, which does not end until you start the next mission, you can wear the Black suit without any damage being done to you. Use this time to clear the city of all gang activity. This may take awhile, but it is easier with the Black suit.
While playing as Black suit Spider-Man, you can find the Metorite Pieces (small rock-like objects surrounded by a purple/pink glow) by listening for a pulsating sound. The louder it gets, the closer you are.
You must first defeat Kraven The Hunter. Use the Black suit and it will be easy. You will then catch up with the new and improved Lizard. Stand by a generator and wait until he is about to strike, then dodge. He will hit the generator and shock himself. This will also shock you. Repeat this until you must counter-attack him and ride his back. Try to balance and he will run into one. When the last one shuts off, you must turn it back on. Go over to the switch and turn it back on. Ride his back one more time to defeat him.
When you are trying to open the boarded up windows, if you are far away from him he will do a long jump towards you; it will then take him a few seconds to recover and attack again. Before he jumps, do not stand in the yellow circles. Instead, stand next to the wall opposite the windows. He will now jump to there, recover, etc. While he is recovering, pull down the boards. When he jumps into the light, attack him. Keep doing this until him and his wife's life runs out to complete the level.
Michael Morbius will fly around, etc. When he lines up, use the Spider-Wall to damage him and he will land. Attack him and repeat this strategy.
Wait until Michael is about to rush you, then open the window. He will be temporarily weakened. Beat him up. Shriek will heal him, losing some of her health. Repeat this until he dies, and she flees the scene.
In your first encounter with Sandman, do not try to attack him, just stay close to him. Counter-attack him several times on different levels to finally battle him. Unfortunately, you must use the Black suit to damage him. Just keep hitting him until you are prompted to give him a bath. Keep repeating this until you defeat him.
Sandman will create a mini-tornado making it so you cannot hit him. Use your Spidey senses to dodge the flying bars and wait until he throws a tank at you. Press Attack when prompted and send it back at him, allowing you to beat him up. He will start up his tornado again and do some damage. Repeat this until he dies.
The second battle with Sandman is easy. Just dodge when your Spidey senses alert you and run to the yellow circles when they appear. Complete the prompts to throw TNT barrels into Sandman. Eventually Harry will kill him, defeating Sandman.
Shriek has a shield, so do not worry about her. Stand next to a satellite and wait for your Spidey senses to activate. Use them and dodge to cause her to damage her crystal. Repeat this until she runs away.
In your final encounter with Shriek, she temporarily takes away your Black suit, and figures from your imagination attack you (your loved ones). You can kill them with one hit, but it is pointless. Wait until the Black suit recharges, then switch over, revealing your true enemies. Attack Shriek until she changes you back to the old Spider-Man. Repeat the previous steps and she will collapse.
Dodge him and wait until he shoots missiles at you. Press Attack to send them back. This will cause him to land, allowing you to hit him. Keep doing this until he dies.
Before this battle, go to the upgrade menu and make sure you have the melee volley attack; then fight. Depending on your health level, you may or may not want to use the power-up. At first, you can easily jump over Venom, confuse him, and take away some of his health. Keep doing this until his black suit begins to "glow". Now when you jump over him, he will run away. This is a good opportunity to use the melee volley attack on him. Keep hitting him until his "glow" gets bigger and eventually Harry will tell you to knock Venom into the air. He will fall back to the ground just as before, easily confused. Repeat this cycle until his health is really low and you can finish him off.
Use the following steps to defeat Venom the first and second time you face him. When you meet Venom for the first time at the construction site, you must defeat him in under five minutes or Mary Jane will die. An easy way to do this is to defeat Venom in version one. It should be quite easy. Version two is slightly harder, but all you have to do is watch his five punch combo. The last punch is his super punch. After he is done with his combo, beat him up. Repeat this until Venom turns into version three. You cannot do much once he is in his full power. Watch carefully and you should see a flashing symbol. Follow what the game instructs you to do and you should win. This works on both fights.
In the final battle with Venom, it is just the two of you. Repeat the previously listed steps to defeat him. When his "glow" is very high, run over to the metal bars and follow the prompt. This will slowly remove the suit off him, eventually killing him.