Successfully complete one of the following tasks to get a trophy:
- The Pride of Fastoon (Platinum): Collect every trophy in Ratchet & Clank: Into the Nexus.
- A Walk in the Park (Bronze): Beat the game on Cadet difficulty.
- The Adventurer (Silver): Beat the game on Hero difficulty.
- The Legend (Gold): Beat the game on Legend difficulty.
- The Show Off (Gold): Beat the game in Challenge Mode.
- Thug Life (Bronze): Win the Destructapalooza Bronze Cup.
- Thug Rookie (Silver): Win the Destructapalooza Silver Cup.
- Thug Champion (Gold): Win the Destructapalooza Gold Cup.
- Vault Cracker (Gold): Unlock the vault on planet Thram.
- In Case of Zombies... (Gold): Purchase all weapons.
- Armored and Dangerous (Silver): Purchase all armor.
- Going Commando (Silver): Upgrade 1 weapon to level 6.
- Up Your Arsenal (Gold): Upgrade all weapons to level 6.
- Gold Rush (Gold): Collect all Gold Bolts.
- Greed (Silver): Collect 1,000,000 bolts over the course of the game.
- Your Worst Nightmare (Silver): Scare at least one of every type of enemy using the Nightmare Box.
- Precious Metal (Bronze): Collect 200 raritanium over the course of the game.
- Exterminator (Bronze): Beat Pest Control with just the Omniwrench.
- Into the Nether Region (Silver): Complete all Netherverse segments.
Additionally, there are four secret trophies:
- Leap for Your Life (Bronze): Grav-Leap to the Thug ship circling the Nebulox Seven.
- Sweet Justice (Bronze): Defeat Neftin Prog.
- Shaky Truce (Bronze): Form an alliance with Neftin Prog.
- Cross the Streams (Bronze): Defeat the Nether Leader and banish his kind.