Tychon's Villa (Location)
A two-loot locale in central Thebes. You'll pass through here during the main quest.
There are an abundance of guards here, but approaching from the north by rooftop will keep you out of their line of sight.
The treasure on the top level is a bit tricky to get to. You can't access it from inside the building, instead you have to slide away the crate blocking a doorway on the southeast side of the upper level.
Smash through the wooden screen behind that, then loot the large white chest for treasure number one.
Enter the actual building through the upper level (through the white curtained doorways), and kill your way down the stairwell to spot the second treasure in a red chest.
Loot it to complete the location.