This drug mission will pop immediately after completing the previous drug mission, Fast.
Talk to Tweak, then go out and try the formula.
This one is pretty straightforward. Angels will rush you- use your enhanced punch to knock them into the fire pits.
If you have trouble making the shot, you can use the same punch key to kick their bodies into the fire, or you can just pick them up and carry them.
Sink six bodies, then kill any remaining Angels on the field. Talk to Tweak when it's all over to earn the enhanced Furious recipe, and complete the mission.