Soured Libations (Main Quest)
One of the three ritual quests in Aaru. Continue this one by following your marker to the House of Libations.
You can reach the tainted wine either by descending the steps inside the villa, or by going down through the hole north of the complex. Snakes should appear as a threat, but there is a bug where they don't always spawn properly here.
Not all the wine-jugs need to be destroyed- use your animus pulse to ID the bad ones (they'll have gold markers above them).
Smash them to complete the mission.